The Science

The Therapeutic Potential of the Ketogenic Diet in Treating Progressive Multiple Sclerosis
Mithu Storoni and Gordon T. Plant

The ketogenic diet improves mitochondrial function and may have potential for treating progressive multiple sclerosis for which no treatment currently exists.

Ketogenic Diets and Physical Performance
Stephen D. Phinney

Impaired physical performance is a common but not obligate result of a low carbohydrate diet. Lessons from traditional Inuit culture indicate that time for adaptation, optimized sodium and potassium nutriture, and constraint of protein to 15–25 % of daily energy expenditure allow unimpaired endurance performance despite nutritional ketosis.

Beyond Weight Loss: A Review of the Therapeutic Uses of Very-Low-Carbohydrate (Ketogenic) Diets
A. Paoli, A. Rubini, J.S. Volek, and K.A. Grimaldi

Ketogenic diets are commonly considered to be a useful tool for weight control and many studies suggest that they could be more efficient than low-fat diets, although there is not concordance in the literature about their absolute effectiveness and even some doubts raised about safety. But there is a ‘hidden face’ of the ketogenic diet: its broader therapeutic action. There are new and exciting scenarios about the use of ketogenic diets, as discussed in this review, in cancer, T2D, PCOS, cardiovascular and neurological diseases.